Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate
Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate
CAS: 352535-68-3
Molecular Formula: C19H21NO3
Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate - Names and Identifiers
Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate - Physico-chemical Properties
| Molecular Formula | C19H21NO3 |
| Molar Mass | 311.37 |
| Melting Point | 160-164°C(lit.) |
| Storage Condition | Room Temprature |
Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate - Risk and Safety
| WGK Germany | 3 |
Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate - Introduction
Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pylrolidinecarboxylate is a chiral compound with the monomer structure formula C19H19NO3. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless or light yellow solid
-Melting point: about 70-75°C
-Solubility: Soluble in some organic solvents, such as alcohols, ethers and ketones, but insoluble in water.
Use:
Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate is mainly used in the field of organic synthesis as a precursor for chiral reagents and catalysts. It can be used for the preparation of chiral compounds with pharmaceutical activity, for example for the synthesis of pharmaceuticals, pesticides and cosmetics.
Preparation Method:
Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate can be prepared by the following steps:
1. methyl benzoate is reacted with 2-diphenylmethyl -1-pyrrolidine methanol to generate 2-diphenylmethyl -1-pyrrolidine methyl ester.
2. A reduction reaction is carried out under alkaline conditions to obtain Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate.
Safety Information:
- Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate shall be handled and stored in accordance with standard laboratory safety procedures.
-It may cause irritation to the eyes, skin and respiratory tract, so it is necessary to wear appropriate protective equipment such as gloves, glasses and masks when handling.
-Avoid inhalation, ingestion and exposure to the compound during use and handling.
-When storing, it should be placed in a dry, cool place, and away from fire and oxidizing agents.
Nature:
-Appearance: Colorless or light yellow solid
-Melting point: about 70-75°C
-Solubility: Soluble in some organic solvents, such as alcohols, ethers and ketones, but insoluble in water.
Use:
Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate is mainly used in the field of organic synthesis as a precursor for chiral reagents and catalysts. It can be used for the preparation of chiral compounds with pharmaceutical activity, for example for the synthesis of pharmaceuticals, pesticides and cosmetics.
Preparation Method:
Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate can be prepared by the following steps:
1. methyl benzoate is reacted with 2-diphenylmethyl -1-pyrrolidine methanol to generate 2-diphenylmethyl -1-pyrrolidine methyl ester.
2. A reduction reaction is carried out under alkaline conditions to obtain Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate.
Safety Information:
- Methyl (2S)-(-)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate shall be handled and stored in accordance with standard laboratory safety procedures.
-It may cause irritation to the eyes, skin and respiratory tract, so it is necessary to wear appropriate protective equipment such as gloves, glasses and masks when handling.
-Avoid inhalation, ingestion and exposure to the compound during use and handling.
-When storing, it should be placed in a dry, cool place, and away from fire and oxidizing agents.
Last Update：2024-04-09 20:49:11
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Product Name: methyl (2S)-2-[hydroxy(diphenyl)methyl]pyrrolidine-1-carboxylate Visit Supplier Webpage Request for quotation
CAS: 352535-68-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 352535-68-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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